All about APDS

Activated PI3K Delta Syndrome

As you or someone you care about learn more about activated PI3K delta syndrome, known as APDS, you may find this website helpful as an additional resource.

APDS (previously known as PASLI Disease) is a rare primary immunodeficiency that was first discovered in 2013. It is caused by genetic variants in either one of two identified genes known as PIK3CD or PIK3R1, which are vital to the development and function of immune cells in the body.

Stay informed

Sign up for APDS updates