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All about APDS

Learn More About Activated PI3K
Delta Syndrome (APDS)

APDS (previously known as PASLI Disease) is a rare primary immunodeficiency that was first characterized in 2013. It is caused by genetic variants in either one of two identified genes known as PIK3CD or PIK3R1, which are vital to the development and function of immune cells in the body.

Hear from APDS
expert Dr Evelyn Wu
Read more about
APDS symptoms
Watch how APDS
affects your body
Learn why genetic
testing matters
Find an APDS
Physician

US Health Professionals

Physician Locator Tool

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